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KMID : 1149220050130020093
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Korean Journal of Oriental Medical Prescription
2005 Volume.13 No. 2 p.93 ~ p.100
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Free Radical Scavenging and Hepatoprotective Effects of Osumokkya-tang
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Jeong Ok-Sam
Yun Young-Gab
Kim Youn-Chul
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Abstract
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In order to find the new hepatoprotective agents preliminary screening of twelve prescriptions which have been used for the treatment of hepatic disease in Oriental traditional medicine has been carried out. Both DPPH free radical scavenging and hepatoprotective effect on tacrine-induced cytotoxicity in Hep G2 cells are performed. Osumokkya-tang which is one of the prescription belongs to interior-warming properties showed the DPPH free radical scavenging effect as well as hepatoprotective activity significantly. It is also suggested that its hepatoprotective effect is derived from Chaenomelis Fructus.
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KEYWORD
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Osumokkya-tang, Chaenomelis Fructus, free radical scavenging, hepatoprotective, Hep G2 cells
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